Ligneous Conjunctivitis in Plasminogen-Deficient Mice
نویسندگان
چکیده
منابع مشابه
Ligneous conjunctivitis in plasminogen-deficient mice.
Ligneous conjunctivitis is a rare form of chronic pseudomembranous conjunctivitis that is associated with systemic membranous pathological changes. A probable link between plasminogen and ligneous conjunctivitis has been indicated by the recent diagnoses of plasminogen deficiency in five patients suffering from ligneous conjunctivitis. The current study reports that plasminogen-deficient mice d...
متن کاملLigneous conjunctivitis: a case report.
BACKGROUND Ligneous conjunctivitis is a rare condition characterized by chronic, recurrent conjunctivitis associated with pseudomembrane, and it may involve other mucous membranes in the mouth, nasopharynx, trachea, and vagina. We examined and treated a case of presumed ligneous conjunctivitis. CASE The patient was a 10-year-old boy. His chief complaints were visual impairment, discomfort, an...
متن کاملCompound-heterozygous mutations in the plasminogen gene predispose to the development of ligneous conjunctivitis.
Homozygous type I plasminogen deficiency has been identified as a cause of ligneous conjunctivitis. In this study, 5 additional patients with ligneous conjunctivitis are examined. Three unrelated patients (1 boy, 1 elderly woman, and 1 man) had plasminogen antigen levels of less than 0.4, less than 0.4, and 2.4 mg/dL, respectively, but had plasminogen functional residual activity of 17%, 18%, a...
متن کاملRAPID COMMUNICATION Homozygous Mutations in the Plasminogen Gene of Two Unrelated Girls With Ligneous Conjunctivitis
Ligneous conjunctivitis is a rare and unusual form of chronic homozygous G r A point mutation was identified in plasminogen exon 7 at position 780 leading to an amino acid pseudomembranous conjunctivitis that usually starts in early infancy. The disease may be associated with pseudoexchange (Arg216 r His). Her healthy sister and her healthy parents were heterozygous for this mutation. The secon...
متن کاملHomozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis.
Ligneous conjunctivitis is a rare and unusual form of chronic pseudomembranous conjunctivitis that usually starts in early infancy. The disease may be associated with pseudomembranous lesions of other mucous membranes in the mouth, nasopharynx, trachea, and female genital tract. We examined two unrelated Turkish girls both suffering from ligneous conjunctivitis and occlusive hydrocephalus. Both...
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ژورنال
عنوان ژورنال: Blood
سال: 1998
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v91.5.1616